Hey guys, Check this out!
New way for gene sequencing and it was design for speed. They're using SOLiD 3 system, and will have more improvements.
The method is called tSMS, True Single Molecules Sequencing.
1. tSMS using single strand 100-200 nt strand, and generate the TAAA tails with a fluorescence A end. These strand served as template.
2. Then these templates will be hybridize to a flow cell, that treated with billions of helico-T capture site.
3. After hybridization, using laser to illuminate the successful hybridize strand. They then using CCD camera to capture the illumination.
4. Then, the fluorescence A will be washed away.
5. Now being the repentance process of adding fluorescence nucleotides A,C,G,T (one at a time) and continue the process of binding, illuminate, visual capturing, and adding next nucleotides again and again, until the end.
It was and article from Wired Science at 28 Oct. Just able to read them recently.
>.< I've being outdated!
Check here.
or Watch the video for more clarity, as my explanation is very sucks most of the times, kekeke..
Enjoy the video.
